Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients

Henrik Reinhard, Ellen Garde, Arnold Skimminge, Per Åkeson, Thomas Z. Ramsøy, Kaj Winther, Hans-Henrik Parving, Peter Rossing, Peter K. Jacobsen

Research output: Contribution to journalJournal articleResearchpeer-review


Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.
Original languageEnglish
JournalCardiovascular Diabetology
Issue number119
Pages (from-to)119-127
Publication statusPublished - Jan 2012


  • 3-D Magnetic Ressonance Imaging
  • Brain Parenchymal Fraction
  • Plasma NT-proBNP
  • Type 2 Diabetes
  • White Matter Hyperintensities

Cite this