Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients

Henrik Reinhard; Ellen  Garde; Arnold Skimminge; Per Åkeson; Thomas Z. Ramsøy; Kaj Winther; Hans-Henrik Parving; Peter Rossing; Peter K. Jacobsen

doi:10.1186/1475-2840-11-119

Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients

Henrik Reinhard, Ellen Garde, Arnold Skimminge, Per Åkeson, Thomas Z. Ramsøy, Kaj Winther, Hans-Henrik Parving, Peter Rossing, Peter K. Jacobsen

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Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.

Original language	English
Journal	Cardiovascular Diabetology
Volume	11
Issue number	119
Pages (from-to)	119-127
ISSN	1475-2840
DOIs	https://doi.org/10.1186/1475-2840-11-119
Publication status	Published - Jan 2012

Keywords

3-D Magnetic Ressonance Imaging
Brain Parenchymal Fraction
Plasma NT-proBNP
Type 2 Diabetes
White Matter Hyperintensities

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/1475-2840-11-119Licence: Unspecified

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503686/pdf/1475-2840-11-119.pdfLicence: Unspecified

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Cite this

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title = "Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients",

abstract = "Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.",

keywords = "3-D Magnetic Ressonance Imaging, Brain Parenchymal Fraction, Plasma NT-proBNP, Type 2 Diabetes, White Matter Hyperintensities",

author = "Henrik Reinhard and Ellen Garde and Arnold Skimminge and Per {\AA}keson and Rams{\o}y, {Thomas Z.} and Kaj Winther and Hans-Henrik Parving and Peter Rossing and {K. Jacobsen}, Peter",

year = "2012",

month = jan,

doi = "10.1186/1475-2840-11-119",

language = "English",

volume = "11",

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journal = "Cardiovascular Diabetology",

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T1 - Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients

AU - Reinhard, Henrik

AU - Garde, Ellen

AU - Skimminge, Arnold

AU - Åkeson, Per

AU - Ramsøy, Thomas Z.

AU - Winther, Kaj

AU - Parving, Hans-Henrik

AU - Rossing, Peter

AU - K. Jacobsen, Peter

PY - 2012/1

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N2 - Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.

AB - Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.

KW - 3-D Magnetic Ressonance Imaging

KW - Brain Parenchymal Fraction

KW - Plasma NT-proBNP

KW - Type 2 Diabetes

KW - White Matter Hyperintensities

U2 - 10.1186/1475-2840-11-119

DO - 10.1186/1475-2840-11-119

M3 - Journal article

SN - 1475-2840

VL - 11

SP - 119

EP - 127

JO - Cardiovascular Diabetology

JF - Cardiovascular Diabetology

IS - 119

ER -