A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study

Leonie Helen Bogl, Kirsten Mehlig, Guiomar Masip, Nathalie Michels, Lucia A. Reisch, Valeria Pala, Angie S. Page, Dénes Molnar, Michael Tornaritis, Toomas Veidebaum, Luis Alberto Moreno, Wolfgang Ahrens, Lauren Lissner, Antje Hebestreit, Jaakko Kaprio, Anna Keski-Rahkonen, Timm Intemann, Paola Russo, Laura Johnson

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Abstract

Objectives: The aim was to investigate associations betweenlifestyle behaviors and BMI z-scores after controlling for potential familialconfounding by comparing sibling pairs.

Methods: Within the European I.Family cohort, weconducted a cross-sectional analysis of 2 subsets of children: 1) among allsame-sex sibling pairs with a maximal age difference of four years (n=1404,mean age 10.7 years) and 2) among overweight-discordant sibling pairs (definedas one overweight or obese sibling with a non-overweight sibling and a BMIdifference of at least 10 percentiles) (n=304, mean age 11.3 years). Physicalactivity was measured by accelerometry and dietary intake by 24-hour dietaryrecalls. Sedentary behaviors and potential covariates were assessed byquestionnaires filled in by the children or their parents. Mixed linearregression was used to examine the associations between sibling differences (?)in lifestyle behaviors and ?BMI z-scores adjusting for ?height, ?age and sex,and the correlations between children within families and countries.

Results: Among all sibling pairs, the siblings withhigher screen time, lower MVPA, less sleep and higher intake of energy andunhealthy foods showed higher BMI z-scores. Within the overweight-discordantpairs, ?screen time and ?MVPA were significantly related to ?BMI z-scores. Ofthe overweight siblings, 37% were on a weight-loss diet, while thecorresponding number in non-overweight siblings was only 12%.

Conclusion: Lifestyle behaviors explain part of BMI z-scoredifferences among siblings raised in the same household. It remains to beexplored whether genetic variants distinguish overweight-discordant siblingsand whether these genes influence food intake or energy expenditure behaviors.This work was done as part of the I.Family Study (http://www.ifamilystudy.eu/).We gratefully acknowledge the financial support of the European Communitywithin the Seventh RTD Framework Programme Contract No. 266044.

Original languageEnglish
Title of host publicationAbstract book for the ISBNPA 2018 Annual Meeting in Hong Kong
Number of pages1
Publisher International Society of Behavioral Nutrition and Physical Activity
Publication date2018
Pages230-231
Article numberO.42.4
ISBN (Print)9781732401105
Publication statusPublished - 2018
EventISBNPA 2018 Annual Meeting: Advancing Behaviour Change Science - Hong Kong, China
Duration: 3 Jun 20186 Jun 2018
Conference number: 17
http://isbnpa2018.venuewest.com/Default.aspx?MenuID=6800

Conference

ConferenceISBNPA 2018 Annual Meeting
Number17
CountryChina
CityHong Kong
Period03/06/201806/06/2018
Internet address

Cite this

Bogl, L. H., Mehlig, K., Masip, G., Michels, N., Reisch, L. A., Pala, V., ... Johnson, L. (2018). A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study. In Abstract book for the ISBNPA 2018 Annual Meeting in Hong Kong (pp. 230-231). [O.42.4] International Society of Behavioral Nutrition and Physical Activity.
Bogl, Leonie Helen ; Mehlig, Kirsten ; Masip, Guiomar ; Michels, Nathalie ; Reisch, Lucia A. ; Pala, Valeria ; Page, Angie S. ; Molnar, Dénes ; Tornaritis, Michael ; Veidebaum, Toomas ; Moreno, Luis Alberto ; Ahrens, Wolfgang ; Lissner, Lauren ; Hebestreit, Antje ; Kaprio, Jaakko ; Keski-Rahkonen, Anna ; Intemann, Timm ; Russo, Paola ; Johnson, Laura. / A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study. Abstract book for the ISBNPA 2018 Annual Meeting in Hong Kong. International Society of Behavioral Nutrition and Physical Activity, 2018. pp. 230-231
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title = "A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study",
abstract = "Objectives: The aim was to investigate associations betweenlifestyle behaviors and BMI z-scores after controlling for potential familialconfounding by comparing sibling pairs.Methods: Within the European I.Family cohort, weconducted a cross-sectional analysis of 2 subsets of children: 1) among allsame-sex sibling pairs with a maximal age difference of four years (n=1404,mean age 10.7 years) and 2) among overweight-discordant sibling pairs (definedas one overweight or obese sibling with a non-overweight sibling and a BMIdifference of at least 10 percentiles) (n=304, mean age 11.3 years). Physicalactivity was measured by accelerometry and dietary intake by 24-hour dietaryrecalls. Sedentary behaviors and potential covariates were assessed byquestionnaires filled in by the children or their parents. Mixed linearregression was used to examine the associations between sibling differences (?)in lifestyle behaviors and ?BMI z-scores adjusting for ?height, ?age and sex,and the correlations between children within families and countries.Results: Among all sibling pairs, the siblings withhigher screen time, lower MVPA, less sleep and higher intake of energy andunhealthy foods showed higher BMI z-scores. Within the overweight-discordantpairs, ?screen time and ?MVPA were significantly related to ?BMI z-scores. Ofthe overweight siblings, 37{\%} were on a weight-loss diet, while thecorresponding number in non-overweight siblings was only 12{\%}.Conclusion: Lifestyle behaviors explain part of BMI z-scoredifferences among siblings raised in the same household. It remains to beexplored whether genetic variants distinguish overweight-discordant siblingsand whether these genes influence food intake or energy expenditure behaviors.This work was done as part of the I.Family Study (http://www.ifamilystudy.eu/).We gratefully acknowledge the financial support of the European Communitywithin the Seventh RTD Framework Programme Contract No. 266044.",
author = "Bogl, {Leonie Helen} and Kirsten Mehlig and Guiomar Masip and Nathalie Michels and Reisch, {Lucia A.} and Valeria Pala and Page, {Angie S.} and D{\'e}nes Molnar and Michael Tornaritis and Toomas Veidebaum and Moreno, {Luis Alberto} and Wolfgang Ahrens and Lauren Lissner and Antje Hebestreit and Jaakko Kaprio and Anna Keski-Rahkonen and Timm Intemann and Paola Russo and Laura Johnson",
year = "2018",
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Bogl, LH, Mehlig, K, Masip, G, Michels, N, Reisch, LA, Pala, V, Page, AS, Molnar, D, Tornaritis, M, Veidebaum, T, Moreno, LA, Ahrens, W, Lissner, L, Hebestreit, A, Kaprio, J, Keski-Rahkonen, A, Intemann, T, Russo, P & Johnson, L 2018, A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study. in Abstract book for the ISBNPA 2018 Annual Meeting in Hong Kong., O.42.4, International Society of Behavioral Nutrition and Physical Activity, pp. 230-231, Hong Kong, China, 03/06/2018.

A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study. / Bogl, Leonie Helen ; Mehlig, Kirsten; Masip, Guiomar; Michels, Nathalie; Reisch, Lucia A.; Pala, Valeria; Page, Angie S.; Molnar, Dénes; Tornaritis, Michael; Veidebaum, Toomas; Moreno, Luis Alberto; Ahrens, Wolfgang; Lissner, Lauren; Hebestreit, Antje; Kaprio, Jaakko; Keski-Rahkonen, Anna; Intemann, Timm; Russo, Paola; Johnson, Laura.

Abstract book for the ISBNPA 2018 Annual Meeting in Hong Kong. International Society of Behavioral Nutrition and Physical Activity, 2018. p. 230-231 O.42.4.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

TY - ABST

T1 - A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study

AU - Bogl, Leonie Helen

AU - Mehlig, Kirsten

AU - Masip, Guiomar

AU - Michels, Nathalie

AU - Reisch, Lucia A.

AU - Pala, Valeria

AU - Page, Angie S.

AU - Molnar, Dénes

AU - Tornaritis, Michael

AU - Veidebaum, Toomas

AU - Moreno, Luis Alberto

AU - Ahrens, Wolfgang

AU - Lissner, Lauren

AU - Hebestreit, Antje

AU - Kaprio, Jaakko

AU - Keski-Rahkonen, Anna

AU - Intemann, Timm

AU - Russo, Paola

AU - Johnson, Laura

PY - 2018

Y1 - 2018

N2 - Objectives: The aim was to investigate associations betweenlifestyle behaviors and BMI z-scores after controlling for potential familialconfounding by comparing sibling pairs.Methods: Within the European I.Family cohort, weconducted a cross-sectional analysis of 2 subsets of children: 1) among allsame-sex sibling pairs with a maximal age difference of four years (n=1404,mean age 10.7 years) and 2) among overweight-discordant sibling pairs (definedas one overweight or obese sibling with a non-overweight sibling and a BMIdifference of at least 10 percentiles) (n=304, mean age 11.3 years). Physicalactivity was measured by accelerometry and dietary intake by 24-hour dietaryrecalls. Sedentary behaviors and potential covariates were assessed byquestionnaires filled in by the children or their parents. Mixed linearregression was used to examine the associations between sibling differences (?)in lifestyle behaviors and ?BMI z-scores adjusting for ?height, ?age and sex,and the correlations between children within families and countries.Results: Among all sibling pairs, the siblings withhigher screen time, lower MVPA, less sleep and higher intake of energy andunhealthy foods showed higher BMI z-scores. Within the overweight-discordantpairs, ?screen time and ?MVPA were significantly related to ?BMI z-scores. Ofthe overweight siblings, 37% were on a weight-loss diet, while thecorresponding number in non-overweight siblings was only 12%.Conclusion: Lifestyle behaviors explain part of BMI z-scoredifferences among siblings raised in the same household. It remains to beexplored whether genetic variants distinguish overweight-discordant siblingsand whether these genes influence food intake or energy expenditure behaviors.This work was done as part of the I.Family Study (http://www.ifamilystudy.eu/).We gratefully acknowledge the financial support of the European Communitywithin the Seventh RTD Framework Programme Contract No. 266044.

AB - Objectives: The aim was to investigate associations betweenlifestyle behaviors and BMI z-scores after controlling for potential familialconfounding by comparing sibling pairs.Methods: Within the European I.Family cohort, weconducted a cross-sectional analysis of 2 subsets of children: 1) among allsame-sex sibling pairs with a maximal age difference of four years (n=1404,mean age 10.7 years) and 2) among overweight-discordant sibling pairs (definedas one overweight or obese sibling with a non-overweight sibling and a BMIdifference of at least 10 percentiles) (n=304, mean age 11.3 years). Physicalactivity was measured by accelerometry and dietary intake by 24-hour dietaryrecalls. Sedentary behaviors and potential covariates were assessed byquestionnaires filled in by the children or their parents. Mixed linearregression was used to examine the associations between sibling differences (?)in lifestyle behaviors and ?BMI z-scores adjusting for ?height, ?age and sex,and the correlations between children within families and countries.Results: Among all sibling pairs, the siblings withhigher screen time, lower MVPA, less sleep and higher intake of energy andunhealthy foods showed higher BMI z-scores. Within the overweight-discordantpairs, ?screen time and ?MVPA were significantly related to ?BMI z-scores. Ofthe overweight siblings, 37% were on a weight-loss diet, while thecorresponding number in non-overweight siblings was only 12%.Conclusion: Lifestyle behaviors explain part of BMI z-scoredifferences among siblings raised in the same household. It remains to beexplored whether genetic variants distinguish overweight-discordant siblingsand whether these genes influence food intake or energy expenditure behaviors.This work was done as part of the I.Family Study (http://www.ifamilystudy.eu/).We gratefully acknowledge the financial support of the European Communitywithin the Seventh RTD Framework Programme Contract No. 266044.

M3 - Conference abstract in proceedings

SN - 9781732401105

SP - 230

EP - 231

BT - Abstract book for the ISBNPA 2018 Annual Meeting in Hong Kong

PB - International Society of Behavioral Nutrition and Physical Activity

ER -

Bogl LH, Mehlig K, Masip G, Michels N, Reisch LA, Pala V et al. A Within-Sibling Pair Analysis of Lifestyle Behaviors and BMI Z-Score in the Multi-center I.Family Cohort Study. In Abstract book for the ISBNPA 2018 Annual Meeting in Hong Kong. International Society of Behavioral Nutrition and Physical Activity. 2018. p. 230-231. O.42.4