Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients

Henrik Reinhard; Ellen  Garde; Arnold Skimminge; Per Åkeson; Thomas Z. Ramsøy; Kaj Winther; Hans-Henrik Parving; Peter Rossing; Peter K. Jacobsen

doi:10.1186/1475-2840-11-119

Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients

Henrik Reinhard, Ellen Garde, Arnold Skimminge, Per Åkeson, Thomas Z. Ramsøy, Kaj Winther, Hans-Henrik Parving, Peter Rossing, Peter K. Jacobsen

Institut for Afsætningsøkonomi

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.

Originalsprog	Engelsk
Tidsskrift	Cardiovascular Diabetology
Vol/bind	11
Udgave nummer	119
Sider (fra-til)	119-127
ISSN	1475-2840
DOI	https://doi.org/10.1186/1475-2840-11-119
Status	Udgivet - jan. 2012

FN’s Verdensmål

Dette resultat bidrager til følgende verdensmål

Adgang til dokumentet

10.1186/1475-2840-11-119Licens: Ikke-specificeret

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503686/pdf/1475-2840-11-119.pdfLicens: Ikke-specificeret

Handle.net

Persistent link

Citationsformater

@article{9f2bddc793d64e41a3284ab3e213838c,

title = "Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients",

abstract = "Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.",

keywords = "3-D Magnetic Ressonance Imaging, Brain Parenchymal Fraction, Plasma NT-proBNP, Type 2 Diabetes, White Matter Hyperintensities",

author = "Henrik Reinhard and Ellen Garde and Arnold Skimminge and Per {\AA}keson and Rams{\o}y, {Thomas Z.} and Kaj Winther and Hans-Henrik Parving and Peter Rossing and {K. Jacobsen}, Peter",

year = "2012",

month = jan,

doi = "10.1186/1475-2840-11-119",

language = "English",

volume = "11",

pages = "119--127",

journal = "Cardiovascular Diabetology",

issn = "1475-2840",

publisher = "BioMed Central",

number = "119",

}

TY - JOUR

T1 - Plasma NT-proBNP and White Matter Hyperintensities in Type 2 Diabetic Patients

AU - Reinhard, Henrik

AU - Garde, Ellen

AU - Skimminge, Arnold

AU - Åkeson, Per

AU - Ramsøy, Thomas Z.

AU - Winther, Kaj

AU - Parving, Hans-Henrik

AU - Rossing, Peter

AU - K. Jacobsen, Peter

PY - 2012/1

Y1 - 2012/1

N2 - Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.

AB - Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.

KW - 3-D Magnetic Ressonance Imaging

KW - Brain Parenchymal Fraction

KW - Plasma NT-proBNP

KW - Type 2 Diabetes

KW - White Matter Hyperintensities

U2 - 10.1186/1475-2840-11-119

DO - 10.1186/1475-2840-11-119

M3 - Journal article

SN - 1475-2840

VL - 11

SP - 119

EP - 127

JO - Cardiovascular Diabetology

JF - Cardiovascular Diabetology

IS - 119

ER -